49ers Injury News: McCaffrey Out Indefinitely with Calf Injury

San Francisco 49ers running back Christian McCaffrey suffered a calf injury in Sunday's game against the Kansas City Chiefs and is expected to miss multiple games.

McCaffrey suffered the injury in the first quarter of the game and was unable to return. He was seen limping off the field and was later ruled out for the game.

The 49ers have not yet announced a timetable for McCaffrey's return, but it is expected that he will miss multiple games. This is a significant blow to the 49ers' offense, as McCaffrey is one of their most important players.

McCaffrey has been one of the most productive running backs in the NFL since entering the league in 2017. He has rushed for over 1,000 yards in each of the past three seasons and has also been a major contributor in the passing game.

The 49ers will now have to rely on other running backs to step up in McCaffrey's absence. Jeff Wilson Jr. is expected to start in McCaffrey's place, but the 49ers may also give more playing time to rookies Jordan Mason and Tyrion Davis-Price.

The 49ers are currently 3-4 and are in need of a win to keep their playoff hopes alive. They will face the Los Angeles Rams on Sunday in a key NFC West matchup.